Researchers:  Dr. Sagiv Shifman and Dr. Miriam Rosenberg

Institute: The Hebrew University of Jerusalem

Opsoclonus Myoclonus Ataxia Syndrome (OMAS) is a rare childhood condition in which the immune system mistakenly attacks the brain, leading to problems with movement, balance, and eye control. It can occur with or without neuroblastoma, making it difficult to diagnose, especially since no lab test currently exists. This research aims to identify the specific immune targets involved in OMAS so doctors can develop a clear diagnostic test, better understand the disease, and improve treatments. In children with OMAS, the immune system appears to be particularly effective at fighting neuroblastoma. Studying this response could reveal new strategies for treating childhood cancers.