Research

We provide funding so the brightest minds in pediatric cancer research can find the next big breakthrough.

What We Fund

What We Fund

To call pediatric cancer research “underfunded” is putting it lightly. Among the 12 different types of childhood cancers – yes, there are 12, with dozens of subtypes – the rarest of cancers go for decades without any progress.

Although we’ve made great strides in treating some childhood cancers in the past 50 years, current treatment protocols cause long-term, chronic health problems for survivors like organ damage, fertility issues, and even secondary cancers.

We seek solutions for the underdogs – the rare childhood cancers – so kids living with cancer don’t just survive, but thrive.

Since 2010, we have awarded $900,000 in Childhood Cancer Research Grants to thirteen institutions worldwide. Our researchers are searching for more effective treatment options, and for a better understanding of how childhood cancers behave.

Institutions Funded

Grant-Distribution-infographic

Our Process

Our Grant Cycle

Past Recipients

Types of Research

Read about our 2014 Childhood Cancer Research Grant Awards!

2014

Translational ResearchGlypican-3 specific T-cells for the Adoptive Immunotherapy of Pediatric Liver Cancers
Andras Heczey M.D.
Texas Children’s Hospital/Baylor College of Medicine

Basic ResearchIdentification and targeting of circulating Ewing’s sarcoma stem cells
Masanori Hayashi, M.D.
Johns Hopkins University

Basic ResearchTranslational ResearchIdentification of novel cdk4/6 effectors in T-cell acute lymphoblastic leukemia
John Carter, M.D., Ph.D.
Fred Hutchinson Cancer Research Center at Seattle Children’s Hospital

Basic ResearchTranslational ResearchDetection of novel autoantibodies in children with OMS
Bethan Lang, M.D.
Oxford University

Translational ResearchClinical ResearchTargets of the Intrathecal B-Cell Response in Pediatric Opsoclonus Myoclonus Syndrome
Gregory Owens, Ph.D.
University of Colorado School of Medicine

2013

Basic ResearchmiRNAs secreted by tumor associated macrophages and resistance in Neuroblastoma
Muller Fabbri M.D., Ph.D.
Saban Research Institute at Children’s Hospital Los Angeles and the University of Southern California *RENEWED!*

Basic ResearchThe role of the de-ubiquitinase USP44 in childhood germ cell tumorigenesis
Ying Zhang, Ph.D.
Mayo Clinic

Translational ResearchDevelopment of anti-tumor molecules targeting the Wilms tumor oncogene, LIN28B
Shilpa Pathak, Ph.D.
Roswell Park Cancer Institute

2012

Basic ResearchRole of the GAB2-SHP2 network in childhood neuroblastoma pathogenesis
Shizen Zhu, M.D., Ph.D.
Dana-Farber Cancer Institute

Clinical ResearchPhase I/II clinical trial evaluating NK cell immunotherapy in relapsed and refractory pediatric solid tumors
Monica Thakar, M.D.
Children’s Hospital of Wisconsin/Medical College of Wisconsin

Basic ResearchElucidating Epigenetic Mechanisms for Therapeutic Targeting in Aggressive Pediatric Cancers
Boris Wilson, Ph.D.
Dana-Farber Cancer Institute

Translational ResearchDevelop Small Molecule Yap Inhibitors to Treat Childhood Cancer
Chungling Yi, Ph.D.
Lombardi Cancer Center at Georgetown University

2011

Clinical ResearchPhase I Dose Escalation Study of Sorafenib/Irinotecan Combination Therapy in Pediatric Relapsed Solid Tumors
Holly Meany, M.D.
Children’s National Medical Center *RENEWED!*

Basic ResearchAlternative Lengthening of Telomeres in Neuroblastoma
Loretta Lau, M.D.
The Children’s Hospital at Westmead, Sydney, Australia

Translational ResearchIdentification of Clinical Biomarkers of Wilms Tumor Using High Accuracy Mass Spectroscopy Urine Proteome Profiling
Elizabeth Mullen, M.D.
Dana-Farber Cancer Institute *RENEWED!*

Key

Basic Research Basic Research helps us build knowledge and understanding of the fundamental aspects of cancer. Sometimes basic research is called “pure” research, as it is not focused on a particular problem or application, but lays the foundation for advancements that can lead to applied gains in the future.

Translational Research Translational Research takes the findings from basic scientific research and attempts to make those findings useful in practical applications. To put it simply, this type of research “translates” science into meaningful health outcomes. It brings science from “bench to bedside.”

Clinical Research Clinical Research determines the safety and effectiveness of medications, devices, diagnostic products or treatment regimens intended for humans. An example is a clinical trial in which children are enrolled to test the efficacy of a newly developed drug.

Apply for a Grant

The deadline for our 2014 Childhood Cancer Research Grant Cycle has passed. Read about our latest award class.

If you have questions about our research grant process or guidelines, please contact Community Affairs Director Megan McMillan at 323.657.5557 or megan@pablove.org.


Featured Events

Featured Events

Los Angeles Gallery Show

WhenDecember 6, 2014

Celebrate our fourth annual gallery show in LA.

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