Shahrzad Bahrampour , Ph.D
The brain is the most complex organ and has a unique defense mechanism, the blood-brain barrier. This barrier protects the brain by limiting the entry of harmful agents from blood. However, that also makes it difficult for therapeutic agents to penetrate, which is a major obstacle in brain tumor therapy. In theory, a targeted ‘leak’ […]
Aasef G. Shaikh MD,PhD
Opsoclonus is the chaotic involuntary shaking of the eyes leading to a significant visual handicap and can be seen in those with various forms of cancers. It is difficult to treat opsoclonus, and available treatments have significant side effects and unpredictable responses. Opsoclonus typically occurs as a result of the body’s attack on one’s own […]
Patricia Denise B. Tiburcio, PhD
Wilms tumors are the most common pediatric kidney cancer and fortunately 90% of children with WT survive 5 years after diagnosis. However, 15% experience relapse, and once this happens, about half of them will likely not recover. Currently, no studies have found an effective approach to overcome chemotherapy resistance. This study will explore ways to […]